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What does aconitine do to the heart?
Aconitine binds with a high affinity to the open state of voltage-sensitive sodium channels at site 2, which causes a persistent activation of the sodium channels and induces arrhythmias due to triggered activity. Hypotension and bradycardia are due to activation of the ventromedial nucleus of the hypothalamus.Jun 30, 2022
Aconitine binds with a high affinity to the open state of voltage-sensitive sodium channels at site 2, which causes a persistent activation of the sodium channels and induces arrhythmias due to triggered activity. Hypotension and bradycardia are due to activation of the ventromedial nucleus of the hypothalamus.Jun 30, 2022